Introduction：
With his knowledge of Genetic Engineering and Immunology, Prof. Nan-chi Chang has ventured his expertise as means for treating actual genetic diseases. After completing his postdoctoral training in the USA, he resolutely returned to the then National Yang-Ming Medical College owing to a high calling, plus a request from our Late President Paul Han (韓偉). Since then, he not only devoted himself to education, but also personally led many teams of National Yang-Ming University to the Orchid Island (Lan-yu) for charity services to patients of various endogenous genetic diseases requiring timely advices and treatments. In this lecture, Prof. Chang will flashback this historical past as a joyful note to you all !!